Group program to prevent postpartum depression, offered in-person or online

Group-based Prevention of Postpartum Depression: In-person vs. Virtual Delivery

NIH-funded research University of Denver (Colorado Seminary) · NIH-11128331

This compares a group program given in person or by video to help pregnant people lower their chance of postpartum depression, offered in English and Spanish.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Denver (Colorado Seminary) NIH-funded
Lab location1 site (Denver, United States)
Project IDNIH-11128331 on NIH RePORTER

What this research studies

If you are pregnant, you could join an evidence-based group program called ROSE delivered either at your prenatal clinic or by video conferencing. Participants are randomly assigned to in-person groups or virtual groups led by the same trained staff and attend a series of sessions before and after birth. The study will track mood and related outcomes during pregnancy and after delivery to see who develops postpartum depression. Researchers will also look at which parts of the program help most and whether some people benefit more than others.

Who could benefit from this research

Good fit: Ideal candidates are pregnant people receiving prenatal care at a participating site who speak English or Spanish and are willing to join group sessions in person or by video.

Not a fit: People who need immediate or intensive treatment for severe depression or psychosis, those who prefer one-on-one therapy, or those without reliable internet for virtual groups may not benefit from this program.

Why it matters

Potential benefit: If successful, this could make an effective prevention program widely available online so more pregnant people can avoid postpartum depression.

How similar studies have performed: Similar group prevention programs like ROSE have shown benefit in reducing postpartum depression, though virtual delivery has not been fully tested in a randomized trial.

Where this research is happening

Denver, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Developmental Delay Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.