Glyphosate's effects on blood sugar regulation through gut bacteria
Official title: Glyphosate impairs glucose homeostasis via gut microbiome induced alterations to bile acid signaling
Funded at University of Arizona · NIH-10873735 · Data updated 2026-11-12
This study is looking at how glyphosate, a common weed killer, might affect blood sugar control by changing the bacteria in our gut, and it's aimed at helping people understand the possible links to type 2 diabetes.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $46,543 |
| NIH project number | 5F31DK137424-02 |
| Project ID | NIH-10873735 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for type 2 diabetes, particularly those with a history of glyphosate exposure or related environmental factors.
✕Less likely to help
Patients who do not have any risk factors for type 2 diabetes or have already been diagnosed with advanced diabetes may not benefit from this research.
What this research studies
This research investigates how glyphosate, a common herbicide, may disrupt glucose regulation in the body by altering the gut microbiome. The study focuses on understanding the connection between glyphosate exposure and changes in bile acid signaling, which is crucial for maintaining healthy blood sugar levels. By examining the effects of glyphosate on gut bacteria and subsequent bile acid production, the research aims to uncover potential pathways that lead to type 2 diabetes. The methodology includes animal models to assess glucose tolerance and microbiome composition following glyphosate exposure.
Why it matters
Potential benefit: If successful, this research could lead to new insights into preventing or managing type 2 diabetes by targeting gut microbiome health.
How similar studies have gone: Other research has indicated that gut microbiome alterations can significantly impact metabolic health, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Meyer, Rachel — University of Arizona
- Study coordinator: Meyer, Rachel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.