GlyGen: building a central, patient-friendly resource on glycans and glycoconjugates
Official title: GlyGen growth and evolution into a central resource for glycans and glycoconjugates
Funded at University of Georgia · NIH-11402746 · Data updated 2026-11-12
This grant supports a central knowledgebase that connects glycan biology data to help researchers better understand how sugars on proteins affect cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Georgia NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project start | September 27, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,072,998 |
| NIH project number | 5R24GM146616-05 |
| Project ID | NIH-11402746 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are patients whose cancers or tissues have known glycosylation alterations or researchers who study glycosylation in cancer biology and could use improved data resources.
✕Less likely to help
Patients without cancers or glycosylation-related conditions may not directly benefit from this knowledgebase.
What this research studies
GlyGen is expanding a comprehensive database that links glycan structures and glycosylation patterns with other biological data to advance cancer research. The project emphasizes making complex glycoscience more accessible so scientists can uncover how sugar molecules influence tumor biology and disease progression. By integrating diverse data types and capturing glycan microheterogeneity, GlyGen aims to reveal new connections between glycans and cancer. This work could inform future studies and eventual therapeutic strategies by providing a richer, organized view of glycosylation in cancer cells and tissues.
Why it matters
Potential benefit: If successful, patients could benefit indirectly from accelerated discoveries in cancer biology that are informed by a clearer understanding of glycans and their role in disease.
How similar studies have gone: Prior efforts to integrate glycobiology data into accessible resources have shown promise in enabling new insights, though comprehensive public glycobiology knowledgebases are relatively unique.
Where this research is happening
-
University of Georgia
Athens, United States Active
Researchers
- Principal investigator: Ranzinger, Rene — University of Georgia
- Study coordinator: Ranzinger, Rene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.