Glycoform production and analysis of human FSH to support fertility research
Official title: Core B: FSH Glycoform Production, Purification, and Analysis
Funded at Wichita State University · NIH-11401770 · Data updated 2026-11-12
A core facility helps produce and purify human FSH glycoforms to support multiple fertility-related projects.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wichita State University NIH-funded |
| Lab location | 1 site (Wichita, United States) |
| Project start | April 15, 2009 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $372,538 |
| NIH project number | 5P01AG029531-14 |
| Project ID | NIH-11401770 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with fertility concerns or researchers studying FSH biology who may benefit from improved reagents and tools for translational research.
✕Less likely to help
Patients seeking direct treatment options are not the immediate target of this core; benefits are primarily through enabling research.
What this research studies
Core B provides essential materials and expertise to support several research aims by producing glycoforms of human FSH and related glycoforms in cells. It develops transfection systems to boost production of mutant glycoforms and supplies cells and antibodies for studying FSH receptor interactions and signaling. Researchers can access specialized reagents, cell lines, and analytical methods to study how different FSH glycoforms affect ovarian cell biology and receptor behavior. This work enables ongoing collaboration across projects focused on fertility and hormone signaling.
Why it matters
Potential benefit: If successful, the work could advance understanding of how different FSH forms influence ovarian function and fertility treatments.
How similar studies have gone: Previous work has shown that specific FSH glycoforms have distinct biological effects, supporting potential translational relevance.
Where this research is happening
-
Wichita State University
Wichita, United States Active
Researchers
- Principal investigator: May, Jeffrey V. — Wichita State University
- Study coordinator: May, Jeffrey V.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.