Global HIV research network for pregnant people, babies, children, and teens
IMPAACT Leadership Group
Testing safer, longer-lasting HIV and TB treatments and approaches to achieve ART-free remission for infants, children, adolescents, and pregnant or postpartum people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11457786 on NIH RePORTER |
What this research studies
If you or your child has HIV or is at risk for TB, this network runs clinical trials and studies aimed at better treatments and prevention. The team tests drug dosing, safety, and how well medicines work in pregnant and postpartum people, infants, children, and adolescents, including lab work like pharmacokinetics. They also try approaches to reduce or stop the need for daily ART by targeting HIV reservoirs, and they develop improved TB prevention, diagnosis, and treatment strategies for these groups. The work is done at clinical sites around the world and includes efforts toward drug licensing and practical use in real-world care.
Who could benefit from this research
Good fit: Ideal candidates are infants, children, adolescents, and pregnant or postpartum people living with HIV, and those with or at risk for TB who can enroll at a participating clinical site.
Not a fit: People who are not living with HIV, not pregnant or postpartum, and not infants, children, or adolescents are unlikely to benefit directly from these studies.
Why it matters
Potential benefit: This work could lead to safer, more durable HIV and TB treatments, new options to reduce or stop daily ART, and better outcomes for pregnant people, babies, children, and adolescents.
How similar studies have performed: Previous pediatric and maternal HIV and TB trials have improved treatment options, though efforts to achieve ART-free remission in children remain relatively novel and experimental.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Nachman, Sharon a — Johns Hopkins University
- Study coordinator: Nachman, Sharon a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.