Global HIV care for pregnant people, babies, children, and teens
IMPAACT Leadership Group
This program tests safer, longer-lasting HIV and TB treatments and ways to safely pause HIV medicine for pregnant people, babies, children, and teens around the world.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11457799 on NIH RePORTER |
What this research studies
You or your child might be invited to clinics where researchers test new antiretroviral medicines, study how drugs behave in pregnant people and children, and try approaches aimed at ART-free remission. The program runs clinical trials and related studies on HIV and tuberculosis prevention, diagnosis, dosing, safety, and long-term outcomes. It focuses on pregnant and postpartum people, infants, children, and adolescents and includes laboratory monitoring, drug level (PK) measurements, and medical follow-up. These studies take place at participating hospitals and clinics in multiple countries through the IMPAACT network.
Who could benefit from this research
Good fit: Ideal candidates are pregnant or postpartum people with HIV and infants, children, or adolescents living with or at high risk for HIV (including those with or at risk for TB) who can attend a participating site and meet study-specific health criteria.
Not a fit: People without HIV, those not in the maternal/pediatric/adolescent age groups, or individuals who do not meet specific trial eligibility criteria or have medical exclusions are unlikely to receive direct benefit from these studies.
Why it matters
Potential benefit: If successful, this work could lead to safer, better-dosed HIV and TB treatments for pregnant people and young people and possibly strategies that reduce or eliminate the need for lifelong ART in some children and teens.
How similar studies have performed: Previous clinical trials have successfully improved dosing and safety of antiretrovirals for pregnant people and children, but ART-free remission approaches remain experimental and are less proven.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Nachman, Sharon a — Johns Hopkins University
- Study coordinator: Nachman, Sharon a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.