Global HIV and TB treatment network for pregnant women, children, and teens
International Maternal, Adolescent and Pediatric Therapeutics Clinical Trials Network
This program tests new and better HIV and TB treatments and care plans for pregnant women, infants, children, and teenagers around the world.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11237077 on NIH RePORTER |
What this research studies
You'll be invited to join clinical trials run by hospitals and clinics that are part of a global network focused on mothers, infants, children, and adolescents affected by HIV and sometimes TB. The network tests pediatric-friendly drug formulations, dosing, prevention strategies, and approaches aimed at ART-free remission while collecting lab samples and health data over time. Studies are coordinated with a central laboratory center to ensure high-quality testing and consistent results across sites. The network also builds research and lab capacity in resource-limited settings so communities with the highest need can benefit.
Who could benefit from this research
Good fit: Ideal participants are pregnant people with HIV, infants and children who are HIV-exposed or HIV-infected, and adolescents with or at high risk for HIV, typically seen at participating clinics worldwide.
Not a fit: People without HIV or those with health issues unrelated to HIV/TB would not directly benefit from these HIV-focused trials.
Why it matters
Potential benefit: If successful, the work could lead to safer, easier-to-use HIV and TB treatments and better care guidelines for pregnant women, babies, children, and teens.
How similar studies have performed: The IMPAACT network has a proven track record: past trials have supported drug approvals and changes to international and US treatment guidelines for pregnant women, children, and adolescents.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Aldrovandi, Grace M — University of California Los Angeles
- Study coordinator: Aldrovandi, Grace M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.