Global collection of human tuberculosis lung tissue and data
A Global Research Resource for Human Tuberculosis
This project builds a worldwide collection of human TB lung tissue and detailed analyses to help researchers develop better tests and treatments for people with tuberculosis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11121101 on NIH RePORTER |
What this research studies
If you donate tissue, doctors will collect lung specimens removed for clinical reasons and link them with medical information while performing detailed pathological, cellular, structural, and genetic analyses. The project will provide those analyses and tissue-access services to researchers around the world to speed studies of active, subclinical, and latent pulmonary TB. Participating hospitals will send specimens to labs that use advanced 3-D imaging and molecular methods to study real human lung disease. Your contribution would help researchers learn how TB affects human lungs in ways that animal models cannot fully reproduce.
Who could benefit from this research
Good fit: Ideal candidates are people with active pulmonary tuberculosis who are undergoing lung surgery or clinically indicated resections and can consent to donate tissue and clinical data.
Not a fit: People without tuberculosis, those not undergoing tissue collection procedures, or anyone seeking immediate personal treatment benefit are unlikely to benefit directly from joining this resource.
Why it matters
Potential benefit: If successful, this resource could help researchers create more accurate diagnostics and more targeted therapies based on real human TB lung biology.
How similar studies have performed: Historically a few human tissue studies informed TB knowledge but were limited, and this larger coordinated human-tissue resource is relatively novel and intended to fill that gap.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Steyn, Adrie Jc — University of Alabama at Birmingham
- Study coordinator: Steyn, Adrie Jc
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.