Global collaboration to understand brain aging and dementia
ENIGMA World Aging Center
This study is looking at how our brains change as we get older, especially for people 65 and up, to find out what affects brain health and helps us understand conditions like Alzheimer's, and your participation can help researchers discover more about how these changes happen.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11053489 on NIH RePORTER |
What this research studies
This research investigates the biological mechanisms influencing brain aging, particularly in individuals aged 65 and older. By leveraging a global network of over 340 institutions across 45 countries, the project aims to pool extensive data and expertise to identify factors that affect brain health. The study focuses on understanding how aging impacts cognitive functions and the development of conditions like Alzheimer's disease. Patients may contribute data that helps researchers uncover personalized predictors of brain structural changes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older, particularly those experiencing cognitive changes or at risk for dementia.
Not a fit: Patients under the age of 65 or those without any cognitive impairment may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for age-related cognitive decline and dementia.
How similar studies have performed: Previous research initiatives like the ENIGMA consortium have shown success in large-scale genetic and neuroimaging studies, indicating a strong potential for this approach.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Thompson, Paul M — University of Southern California
- Study coordinator: Thompson, Paul M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.