Glasses that protect night-shift nurses' sleep hormones while keeping vision clear

Filtered eyewear to prevent light-induced melatonin suppression while maintaining visual performance and alertness in night-shift working nurses

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-11118650

Seeing if wearing an orange blue-blocking filter over one eye helps night-shift nurses keep melatonin levels steady while preserving vision and alertness.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11118650 on NIH RePORTER

What this research studies

You would try wearing special orange, blue-blocking filters either over one eye or both while researchers measure your melatonin, vision performance, and subjective sleepiness in a lab setting. Next, they will test the filters in a simulation center where nurses perform depth-perception tasks like IV or catheter placement while wearing the eyewear. Finally, the study will follow nurses working real night shifts at Mount Sinai and a partner hospital in Indiana to measure melatonin and on-shift performance with the filters. The team will compare monocular (one-eye) filtering, binocular filtering, and no filter to see which balances hormone protection with safe, comfortable vision.

Who could benefit from this research

Good fit: Ideal participants are adult nurses or other healthcare workers who regularly work night shifts and are willing to try wearing the filter eyewear during lab, simulation, and real-shift testing.

Not a fit: People who do not work night shifts, cannot tolerate wearing a monocular filter, or who require full unfiltered binocular color vision for safety-sensitive tasks may not benefit.

Why it matters

Potential benefit: If successful, this could help night-shift workers protect their sleep hormones and reduce health risks from nighttime light without hurting job performance or alertness.

How similar studies have performed: Previous studies show blue-blocking lenses and monocular light exposure can preserve nighttime melatonin, but using a single-eye filter while checking real-world nursing tasks is a newer, practical test.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.