Gentle throat vibration therapy for stubborn chronic cough
Vibrotactile stimulation of the larynx for refractory chronic cough
['FUNDING_OTHER'] · UNIVERSITY OF MINNESOTA · NIH-11170705
This project uses gentle vibration applied to the throat to try to reduce long-lasting cough in people whose cough hasn't improved with usual treatments.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-11170705 on ClinicalTrials.gov |
What this research studies
You would receive gentle vibrotactile stimulation applied to the larynx (throat) with varying dose levels to find the most helpful schedule. The team will track cough frequency, cough-related quality of life, and any side effects during and after each dosing condition. This work builds on early results that showed fewer coughs and better quality of life with similar vibration therapy. If a best dose is identified, it could guide larger trials of this approach.
Who could benefit from this research
Good fit: Ideal candidates are adults with persistent chronic cough that has not improved after standard treatments.
Not a fit: Patients whose cough is caused by an easily treatable condition or who cannot tolerate or attend in-person throat stimulation visits may not receive benefit from this project.
Why it matters
Potential benefit: If successful, the treatment could lower how often you cough and improve daily quality of life for people with refractory chronic cough.
How similar studies have performed: Early pilot findings reported improvements in cough counts and cough-related quality of life, but the approach remains early and needs dose-finding confirmation.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MISONO, STEPHANIE — UNIVERSITY OF MINNESOTA
- Study coordinator: MISONO, STEPHANIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.