Genome center supporting All of Us participants
Broad-Color: The Genome Center for the Future of All of Us
This project will provide large-scale genome sequencing and clinical genetic testing for All of Us participants to help researchers and participants learn more about health and disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11379624 on NIH RePORTER |
What this research studies
Teams at the Broad Institute and Color will sequence genomes and run clinical genetic tests for people enrolled in the All of Us program. They will return clinical results when appropriate and plan to expand data types by adding multi‑omics and longitudinal measurements. The partners aim to use high-volume processing and cost-sharing to lower per-sample costs and meet All of Us commitments. The data generated will be shared with approved researchers to speed discoveries about disease risk, diagnosis, and treatment.
Who could benefit from this research
Good fit: Ideal candidates are people already enrolled in the All of Us program or those eligible to join who are willing to provide biospecimens and health information.
Not a fit: People who are not enrolled in All of Us or who do not want their genetic data used for research are unlikely to receive direct benefits from this project.
Why it matters
Potential benefit: If successful, patients could get more accurate genetic risk information, improved disease markers, and research findings that inform better diagnosis and treatments.
How similar studies have performed: Broad and Color have previously sequenced and returned clinical results for hundreds of thousands of people, so this builds on well-established large-scale genomic work.
Where this research is happening
Cambridge, United States
- Broad Institute, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Gabriel, Stacey — Broad Institute, INC.
- Study coordinator: Gabriel, Stacey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.