Genetics-based smoking-cessation care for American Indian and Alaska Native communities
Precision pharmacogenomics and Indigenous research: A novel approach to tobacco cessation efficacy in American Indian communities
['FUNDING_OTHER'] · UNIVERSITY OF COLORADO DENVER · NIH-11169069
This project develops personalized quit-smoking plans using genetic and epigenetic information for American Indian and Alaska Native people.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11169069 on ClinicalTrials.gov |
What this research studies
You would be invited to share health information and a small genetic sample so researchers can learn how nicotine is processed in American Indian and Alaska Native bodies. The team will use genome-wide and epigenome-wide analyses together with community guidance to find factors tied to nicotine metabolism and quitting success. Work is being done in partnership with tribal communities and the Strong Heart Study to keep the approach respectful and relevant. Results will support culturally appropriate ways to match medications or other supports to people who smoke.
Who could benefit from this research
Good fit: Ideal candidates are American Indian and Alaska Native adults who smoke and are willing to provide health information and a small genetic sample and to work with community partners on culturally respectful approaches.
Not a fit: People who are not American Indian or Alaska Native, who are not current smokers, or who do not want to provide genetic samples are unlikely to receive direct benefit from this project.
Why it matters
Potential benefit: If successful, this could lead to more effective, culturally tailored quitting treatments and fewer tobacco-related illnesses in American Indian and Alaska Native communities.
How similar studies have performed: Genetics-guided approaches to smoking cessation have shown promise in other populations, but they are largely untested in American Indian and Alaska Native communities.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CLAW, KATRINA G — UNIVERSITY OF COLORADO DENVER
- Study coordinator: CLAW, KATRINA G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.