Genetics and memory in Mexican teachers
Mexican Teachers Cohort Study: Genetics and Cognitive Function
['FUNDING_U01'] · RUSH UNIVERSITY MEDICAL CENTER · NIH-11199000
This project will add genetic data from thousands of Mexican women teachers to Alzheimer's research to find genes linked to thinking and memory in older Mexican and Hispanic adults.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RUSH UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-11199000 on ClinicalTrials.gov |
What this research studies
You would be part of a large effort that shares genetic information and cognitive data from the Mexican Teachers Cohort with the Alzheimer's Disease Sequencing Project. The team plans to contribute nearly 20,000 genome-wide scans and 5,000 whole genomes and combine them with other datasets to look for genetic factors tied to memory and dementia. The cohort follows female teachers across 12 Mexican states and includes ancestry information that helps researchers understand risk in Mexican and US Hispanic populations. Findings aim to clarify why dementia may start earlier or last longer in some Hispanic groups and to guide future prevention or treatment work.
Who could benefit from this research
Good fit: Ideal candidates are older Mexican women—especially current or former teachers—who can provide health information and a DNA sample for genetic analysis.
Not a fit: Men, people of non-Mexican ancestry, or younger adults who are not part of the Mexican Teachers Cohort may not directly benefit from findings focused on Mexican women.
Why it matters
Potential benefit: If successful, this work could identify genetic risk or protective factors that help tailor prevention or treatment strategies for Mexican and Hispanic communities.
How similar studies have performed: Large Alzheimer's genetics projects have identified risk genes in predominantly European groups, and adding diverse cohorts like this is a newer approach expected to reveal novel, population-specific findings.
Where this research is happening
CHICAGO, UNITED STATES
- RUSH UNIVERSITY MEDICAL CENTER — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GRODSTEIN, FRANCINE — RUSH UNIVERSITY MEDICAL CENTER
- Study coordinator: GRODSTEIN, FRANCINE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.