Genetics and biomarker hub for diverse Alzheimer’s samples
Core D: Genomics and Biomarker Core
This project gathers and shares DNA and blood test data from people with Alzheimer’s, focusing on African, African American, and Cuban communities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11126006 on NIH RePORTER |
What this research studies
From a patient's view, the team collects blood and DNA samples from thousands of people and stores them securely so they can be used for research. They run genetic testing across the genome and measure Alzheimer's-related proteins in the blood for a subset of participants. The core links these new data with existing datasets and standardizes the analysis so researchers can compare results across groups. All data and biological materials are prepared to be shared with collaborating projects and public repositories to speed up discoveries.
Who could benefit from this research
Good fit: Ideal participants are people with Alzheimer’s disease or related dementia—especially those of African, African American, or Cuban ancestry—who can provide blood or DNA samples at participating sites.
Not a fit: People who cannot give blood or DNA, live far from the participating study sites, or are outside the targeted ancestral groups may not be eligible or benefit directly from this core.
Why it matters
Potential benefit: If successful, this work could reveal genetic and blood‑biomarker differences across ancestral groups that help improve diagnosis, risk prediction, and development of treatments for more diverse patients.
How similar studies have performed: Large genetic and plasma‑biomarker studies have previously found Alzheimer’s risk markers, but combining high‑quality genomics and blood biomarkers in underrepresented African and Afro‑descendant populations is relatively new.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Griswold, Anthony John — University of Miami School of Medicine
- Study coordinator: Griswold, Anthony John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.