Genetic sequencing and result reporting support for All of Us participants
All of Us at the Baylor-Hopkins Clinical Genome Center
This project provides DNA sequencing, genotyping, and genetic result reports for people enrolled in the All of Us Research Program.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11378924 on NIH RePORTER |
What this research studies
If you are an All of Us participant, this program will process your DNA using short-read whole genome sequencing and genotyping arrays and create genetic interpretation reports. The team at Baylor, Johns Hopkins, and UTSPH will use automated literature scanning and re-analysis tools so variant findings can be updated over time. The project includes validating sequencing on a clinical platform for regulatory approval and reprocessing large numbers of samples to improve data quality. Your data and results help improve variant interpretation for the broader All of Us community.
Who could benefit from this research
Good fit: Ideal candidates are people enrolled in the All of Us Research Program who have provided or are willing to provide DNA samples.
Not a fit: People who are not enrolled in All of Us or whose genetic variants cannot be interpreted with current knowledge may not receive a direct personal benefit.
Why it matters
Potential benefit: Participants could receive clearer genetic findings and updated reports that may identify medically relevant variants.
How similar studies have performed: Large-scale genotyping and sequencing efforts in All of Us and other cohorts have successfully returned genetic findings, while automated reanalysis and some regulatory validations are newer enhancements.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Gibbs, Richard a — Baylor College of Medicine
- Study coordinator: Gibbs, Richard a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.