Gateway Exposome Hub for Alzheimer's and related dementias
Gateway Exposome Coordinating Center (GECC) For AD/ADRD Research
This project builds a central hub to standardize and share information about life-course environmental and social factors that can affect Alzheimer's and related dementias.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11139481 on NIH RePORTER |
What this research studies
The team will bring together researchers, community groups, and experts to set priorities and agree on which environmental and social measures matter most for Alzheimer's risk, resilience, and disparities. They will create harmonized measures across six areas—physical environment, social environment, policies, community services, extreme weather events, and life experiences—and produce guidance and best practices for using those measures. The center will use and expand the Gateway to Global Aging Data platform to host, link, and share exposome data from different studies and cohorts. The goal is to make it easier for researchers to combine and compare data so findings about exposures and dementia are more reliable and useful.
Who could benefit from this research
Good fit: People most directly involved would include older adults with Alzheimer's or related dementias, people at risk, caregivers, and members of existing research cohorts who can share exposure and life-course information.
Not a fit: People seeking immediate treatments or direct clinical benefits are unlikely to receive personal benefit from this coordinating and data-harmonization effort.
Why it matters
Potential benefit: If successful, this could help researchers identify environmental and social factors that lead to better prevention strategies and fairer care for people with Alzheimer's and related dementias.
How similar studies have performed: Similar harmonization efforts like the Gateway to Global Aging Data have advanced aging research, but applying harmonized exposome measures specifically to Alzheimer's is a newer and still-developing approach.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Lee, Jinkook — University of Southern California
- Study coordinator: Lee, Jinkook
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.