NIH-funded research NIH-funded research

Game that uses muscle signals to retrain arm and hand movements after stroke

Official title: EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke

Funded at Ralph H Johnson VA Medical Center · NIH-11310727 · Data updated 2026-11-12

This project uses a computer game controlled by your arm muscle electrical signals to help people who have persistent hand or arm problems after a stroke regain more normal movement.

More Stroke research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRalph H Johnson VA Medical Center
NIH-funded
Lab location1 site (Charleston, United States)
Project startApril 1, 2023
Project endMarch 31, 2027
Funding year2026
NIH project number5I01RX004523-04
Project IDNIH-11310727 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people who have had a stroke and still have difficulty using their hand or arm despite prior rehabilitation, but who can produce some voluntary muscle signals in the affected limb.

Less likely to help

People with no usable muscle signals in the affected arm, severe cognitive impairment preventing game participation, or unstable medical issues are unlikely to benefit or be eligible.

What this research studies

The system reads electrical activity from muscles in your affected arm and maps those signals to move a cursor in a 2-dimensional game so you can practice more normal muscle patterns. In earlier work, target muscle patterns were taken from the non-affected arm and people used their affected arm to match those patterns while playing games. Twenty stroke survivors showed improved arm function after nine game sessions in preliminary testing. The team plans to make the control more intuitive and expand the game into a full therapy program that trains multiple muscles and movement links.

Why it matters

Potential benefit: If successful, this could improve hand and arm function and daily independence by retraining abnormal muscle activation that standard therapy may miss.

How similar studies have gone: A small preliminary trial with 20 stroke survivors showed significant functional improvements after nine game sessions, so the approach is promising but still early-stage.

Where this research is happening

  • Ralph H Johnson VA Medical Center
    Charleston, United States
    Active

Researchers

  • Principal investigator: Dean, Jesse C. — Ralph H Johnson VA Medical Center
  • Study coordinator: Dean, Jesse C.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.