NIH-funded research R01 grant

Frontal-thalamo-cerebellar brain circuits and attention in kids with ADHD

Official title: Frontal-thalamo-cerebellar circuitry of attention deficit via imaging-genetic-environmental analyses

Funded at Georgia State University · NIH-11406022 · Data updated 2026-11-12

This NIH grant explores how brain networks involved in attention develop in adolescents with ADHD using brain scans, genetics, and environmental data.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia State University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startAugust 16, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$351,000
NIH project number5R01MH130595-04
Project IDNIH-11406022 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents with ADHD or those at risk, who can contribute brain imaging data, cognitive assessments, and environmental information.

Less likely to help

Participants outside the adolescent age range or without ADHD symptoms may not directly benefit.

What this research studies

The project uses brain imaging, genetics, and environmental information from the ABCD study to understand how the frontal-thalamo-cerebellar circuits relate to attention and ADHD symptoms over time. Advanced computer methods will link image features with neurocognitive performance like attention, memory, processing speed, and response variability. The study tracks changes over two years to see how brain circuitry and symptoms co-evolve, with a focus on adolescents in a real-world setting. By combining multimodal data, researchers aim to uncover mechanisms that could inform future interventions for ADHD.

Why it matters

Potential benefit: Gains could lead to better-targeted, brain-based approaches for diagnosing and treating ADHD in youth.

How similar studies have gone: Previous work shows brain network differences in ADHD, and this study builds on that with multimodal data and longitudinal analysis.

Where this research is happening

  • Georgia State University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Liu, Jingyu — Georgia State University
  • Study coordinator: Liu, Jingyu

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.