Freezing zebrafish embryos and larvae for research purposes
Official title: Cryopreservation of zebrafish larvae and embryos for biomedical research
Funded at Massachusetts General Hospital · NIH-10866392 · Data updated 2026-11-12
This study is working on a way to safely freeze zebrafish embryos and larvae so that researchers can keep important zebrafish lines for future experiments without worrying about losing them, and it will also teach other labs how to do this freezing technique.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $642,272 |
| NIH project number | 5R24OD034189-02 |
| Project ID | NIH-10866392 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include researchers and laboratories that utilize zebrafish as a model organism in their studies.
✕Less likely to help
Patients who do not work with zebrafish or are not involved in biomedical research may not receive any direct benefit from this research.
What this research studies
This research focuses on developing a method to freeze zebrafish embryos and larvae, which are widely used in biomedical research. By creating a reliable cryopreservation protocol, the project aims to help researchers store and preserve valuable zebrafish lines without the risk of losing them due to facility issues or genetic changes. The research will also involve training other laboratories on how to implement this freezing technique effectively. This approach could significantly enhance the availability of zebrafish models for various studies in biology and medicine.
Why it matters
Potential benefit: If successful, this research could provide a sustainable way to preserve important zebrafish models, facilitating advancements in biomedical research and therapeutic discoveries.
How similar studies have gone: While sperm cryopreservation in fish has seen success, the cryopreservation of embryos is still facing challenges, making this research a novel and potentially groundbreaking effort.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Tessier, Shannon Noella — Massachusetts General Hospital
- Study coordinator: Tessier, Shannon Noella
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.