NIH-funded research R01 grant

Fortified balanced energy‑protein supplement for pregnant and breastfeeding mothers to support baby growth in southern Nepal

Official title: Balanced Energy Protein Supplement in Early Lactation on Infant Growth in Southern Nepal

Funded at Johns Hopkins University · NIH-11159542 · Data updated 2026-11-12

Daily fortified food given to pregnant and/or breastfeeding women in Nepal to help their babies grow better during the first six months of life.

More Lactation research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startSeptember 19, 2022
Project endJuly 31, 2027
Funding year2025
Award (this year)$612,145
NIH project number5R01HD109385-04
Project IDNIH-11159542 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant women and/or breastfeeding mothers in southern Nepal, especially those with low nutritional status, and their infants in the first six months of life are the ideal candidates.

Less likely to help

People who are not pregnant or breastfeeding, infants older than six months, or mothers with adequate nutrition are unlikely to benefit from this specific supplementation approach.

What this research studies

If you join, you or your baby may receive a daily ready-to-use fortified balanced energy‑protein (BEP) supplement during pregnancy, lactation, or both. The project compares groups who receive the supplement at different times to track infant growth through six months and to monitor mothers' nutritional status. Researchers will collect breast milk, blood, and stool samples from mothers and infants in a biospecimen sub-study to look at nutrients, inflammation, milk composition, and the gut microbiome. The work is based in southern Nepal and run by an international team from Johns Hopkins.

Why it matters

Potential benefit: If successful, the supplementation could improve mothers' nutrition and reduce early infant growth faltering, lowering the risk of stunting and its long-term effects.

How similar studies have gone: Fortified supplements in pregnancy have shown benefits for birth outcomes in some prior trials, but giving this specific BEP supplement during lactation is less well studied and somewhat novel.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Erchick, Daniel Joseph — Johns Hopkins University
  • Study coordinator: Erchick, Daniel Joseph

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.