Following babies exposed to opioids before birth
HEAL Initiative: Antenatal Opioid Exposure Longitudinal Study Consortium
This project follows babies who were exposed to opioids before birth to learn how it affects their brain development and overall health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11145224 on NIH RePORTER |
What this research studies
Neonatal Opioid Withdrawal Syndrome (NOWS) is a serious health issue for many newborns in the USA. We don't fully understand how being exposed to opioids before birth affects a baby's brain and development over time. This project, called OBOE, carefully follows babies from birth up to two years of age, including those exposed to opioids and those not exposed. We collect detailed information on their development, brain imaging, home life, and their mother's well-being to better understand these effects.
Who could benefit from this research
Good fit: This project focuses on infants who were exposed to opioids before birth, as well as a comparison group of infants who were not exposed.
Not a fit: Patients who are not infants or whose mothers did not have opioid exposure during pregnancy would not directly benefit from participating in this specific follow-up.
Why it matters
Potential benefit: If successful, this work could help us better understand the long-term effects of opioid exposure on children, leading to improved care and support for affected families.
How similar studies have performed: While previous smaller studies have explored aspects of antenatal opioid exposure, this project aims to provide more comprehensive and controlled data on long-term neurodevelopmental outcomes.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Demauro, Sara Bonamo — Children's Hosp of Philadelphia
- Study coordinator: Demauro, Sara Bonamo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.