Flexible high-resolution thin-film electrodes to improve epilepsy diagnosis
Advancing Epilepsy Diagnosis with Flexible, High-Resolution Thin-Film Electrodes
Using flexible, very thin brain electrodes to help people with focal epilepsy whose seizure sources are hard to find.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11031282 on NIH RePORTER |
What this research studies
You'll be offered a new kind of flexible, thin electrode that can be placed on or near the brain to record seizures across a wider area with finer detail than current devices. The team aims to turn modern thin-film technology into implantable electrodes designed to cause less pain, swelling, and inflammation than standard subdural grids while sampling broader regions than stereoEEG. This phased UG3/UH3 clinical project brings together surgeons, engineers, and industry partners at centers like NYU, Duke, and the University of Utah to test safety, signal quality, and implantation procedures. Device recordings would be used to more precisely locate seizure origins to guide safer, more effective epilepsy surgery.
Who could benefit from this research
Good fit: People with uncontrolled focal epilepsy whose seizure focus is poorly localized and who are being considered for invasive monitoring or epilepsy surgery.
Not a fit: People with generalized epilepsy, those who are not surgical candidates, or those unable or unwilling to undergo an implant procedure are unlikely to benefit from this project.
Why it matters
Potential benefit: If successful, this could help patients with hard-to-localize focal epilepsy achieve long-term seizure freedom by improving seizure mapping and reducing surgical risks.
How similar studies have performed: Similar high-density and thin-film electrode approaches have shown promise in laboratory and early feasibility work, but broad clinical effectiveness remains to be proven.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Friedman, Daniel — New York University School of Medicine
- Study coordinator: Friedman, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.