Finding ways to reduce drug overdose deaths through community efforts and new strategies.

Reversing Overdose Epidemics through Simulation, Collaboration, and Unified Efforts (RESCUE)

NIH-funded research University of Minnesota · NIH-11059402

This study is working to help people, especially in minority communities, who are affected by drug overdoses by creating and testing new ways to provide life-saving resources and support, like distributing naloxone and setting up overdose prevention centers.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-11059402 on NIH RePORTER

What this research studies

This research focuses on addressing the escalating drug overdose crisis in the U.S., particularly among racial and ethnic minority populations. It aims to develop and implement tailored harm reduction strategies, such as naloxone distribution and overdose prevention centers, in six different jurisdictions. By collaborating with health departments and community partners, the project will assess the effectiveness and cost-effectiveness of these interventions to create a comprehensive response to the overdose epidemic. Patients may benefit from improved access to life-saving resources and support systems designed specifically for their communities.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk of opioid overdose, particularly those from African American, American Indian/Alaska Native, and other minority communities.

Not a fit: Patients who are not at risk of opioid overdose or do not belong to the targeted demographic groups may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce overdose deaths and improve health outcomes for vulnerable populations.

How similar studies have performed: Previous research has shown success in optimizing naloxone distribution strategies, indicating that similar approaches may be effective in addressing the overdose crisis.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.