NIH-funded research NIH-funded research

Finding ways to reduce drug overdose deaths through community efforts and new strategies.

Official title: Reversing Overdose Epidemics through Simulation, Collaboration, and Unified Efforts (RESCUE)

Funded at University of Minnesota · NIH-11059402 · Data updated 2026-11-12

This study is working to help people, especially in minority communities, who are affected by drug overdoses by creating and testing new ways to provide life-saving resources and support, like distributing naloxone and setting up overdose prevention centers.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Minnesota
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startSeptember 15, 2024
Project endJuly 31, 2028
Funding year2024
Award (this year)$1,158,064
NIH project number1R33DA062346-01
Project IDNIH-11059402 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals at risk of opioid overdose, particularly those from African American, American Indian/Alaska Native, and other minority communities.

Less likely to help

Patients who are not at risk of opioid overdose or do not belong to the targeted demographic groups may not receive benefit from this research.

What this research studies

This research focuses on addressing the escalating drug overdose crisis in the U.S., particularly among racial and ethnic minority populations. It aims to develop and implement tailored harm reduction strategies, such as naloxone distribution and overdose prevention centers, in six different jurisdictions. By collaborating with health departments and community partners, the project will assess the effectiveness and cost-effectiveness of these interventions to create a comprehensive response to the overdose epidemic. Patients may benefit from improved access to life-saving resources and support systems designed specifically for their communities.

Why it matters

Potential benefit: If successful, this research could significantly reduce overdose deaths and improve health outcomes for vulnerable populations.

How similar studies have gone: Previous research has shown success in optimizing naloxone distribution strategies, indicating that similar approaches may be effective in addressing the overdose crisis.

Where this research is happening

  • University of Minnesota
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Zang, Xiao — University of Minnesota
  • Study coordinator: Zang, Xiao

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.