Finding ways to prevent malaria outbreaks after severe flooding
Official title: After the flood: Optimal strategies to prevent malaria epidemics caused by severe flooding
Funded at Univ of North Carolina Chapel Hill · NIH-10925374 · Data updated 2026-11-12
This study is looking at ways to stop malaria outbreaks that can happen after heavy flooding in rural areas, and it will test a special prevention method to help keep people safe from malaria in affected communities.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 8, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $972,733 |
| NIH project number | 5R01AI173558-02 |
| Project ID | NIH-10925374 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals living in rural areas prone to flooding, particularly children and adults at risk of malaria.
✕Less likely to help
Patients who do not live in flood-prone areas or those who are not at risk for malaria may not benefit from this research.
What this research studies
This research investigates how to effectively prevent malaria epidemics that can occur after severe flooding, particularly in rural areas. It builds on previous successful interventions by testing a targeted malaria chemoprevention strategy combined with larval source management. The study will involve a cluster randomized trial across multiple villages to assess the effectiveness of these interventions in reducing malaria incidence during critical periods following flooding. Patients in affected communities may receive preventive treatments to help protect them from malaria.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of malaria in communities affected by severe flooding.
How similar studies have gone: Previous pilot interventions have shown promising results, indicating that similar approaches can effectively reduce malaria incidence.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Boyce, Ross Mathew — Univ of North Carolina Chapel Hill
- Study coordinator: Boyce, Ross Mathew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.