Finding ways to prevent complications in patients with cirrhosis
Strategies and Therapies for Outcomes Prevention in Cirrhosis: The STOP-C Liver Cirrhosis Network
This study is looking for people with compensated cirrhosis to learn more about their health and behaviors, so we can better predict who might face complications and see if long-term use of statins can help prevent liver problems, all while keeping track of their progress in everyday life.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11169442 on NIH RePORTER |
What this research studies
This research focuses on creating a cohort of patients with compensated cirrhosis to gather data on their clinical, behavioral, and metabolic characteristics. By analyzing this information, the study aims to develop prediction models that can identify patients at risk of disease progression and complications. Additionally, it will explore the effectiveness of long-term statin therapy in preventing liver-related issues, independent of its cholesterol-lowering effects. Patients will be monitored through both direct clinical assessments and electronic health records to validate findings in real-world settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with compensated cirrhosis, including those with non-alcoholic steatohepatitis (NASH), alcoholic liver disease (ALD), cholestatic, and cryptogenic cirrhosis.
Not a fit: Patients with decompensated cirrhosis or those who do not have liver-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing serious complications in patients with cirrhosis, potentially enhancing their quality of life and survival rates.
How similar studies have performed: Previous research has shown promise in using cohort studies and electronic health records to improve patient outcomes in liver diseases, indicating that this approach may yield valuable insights.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Brown, Robert S — Weill Medical Coll of Cornell Univ
- Study coordinator: Brown, Robert S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.