Finding ways to prevent complications in patients with cirrhosis
Strategies and Therapies for Outcomes Prevention in Cirrhosis: The STOP-C Liver Cirrhosis Network
This study is looking for people with compensated cirrhosis to help gather information about their health and experiences, so researchers can find better ways to predict when their condition might worsen and see if long-term use of statins can help prevent serious complications.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10909129 on NIH RePORTER |
What this research studies
This research focuses on creating a cohort of patients with compensated cirrhosis to gather clinical, behavioral, and biomarker data. By analyzing this data, the researchers aim to develop prediction models that can forecast clinical decompensation and validate the effectiveness of long-term statin therapy in preventing complications like hepatic decompensation and hepatocellular carcinoma. Patients will be monitored for their health outcomes, and their experiences will contribute to a better understanding of cirrhosis progression and treatment efficacy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with compensated cirrhosis, including those with non-alcoholic steatohepatitis (NASH), alcoholic liver disease (ALD), cholestatic, and cryptogenic cirrhosis.
Not a fit: Patients with decompensated cirrhosis or those not diagnosed with any form of cirrhosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing serious complications in patients with cirrhosis.
How similar studies have performed: Previous research has shown promise in using cohort studies and biomarker analysis to improve outcomes in liver disease, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Brown, Robert S — Weill Medical Coll of Cornell Univ
- Study coordinator: Brown, Robert S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.