Finding ways to prevent brain problems in young children with type 1 diabetes
Official title: Identifying Targets for Preventing Neurocognitive Complications in Youth with T1D
Funded at Joslin Diabetes Center · NIH-10975286 · Data updated 2026-11-12
This study is looking at how type 1 diabetes affects the brain development of young kids aged 4 to 8, and it aims to find out what helps or harms their brain health, so we can better understand and support children with this condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Joslin Diabetes Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 22, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $320,972 |
| NIH project number | 1U01DK140790-01 |
| Project ID | NIH-10975286 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 4 to 8 years who have recently been diagnosed with type 1 diabetes.
✕Less likely to help
Patients who are older than 8 years or those without a diagnosis of type 1 diabetes may not benefit from this research.
What this research studies
This research focuses on understanding how type 1 diabetes (T1D) affects brain development in young children, particularly those diagnosed between the ages of 4 and 8. The team at Joslin Diabetes Center and Boston Children's Hospital will evaluate neurocognitive complications and identify factors that may protect or risk brain health in these children. By recruiting a diverse group of participants, including those from under-resourced backgrounds, the study aims to gather comprehensive data on the impacts of T1D on cognitive function and brain development. The research will utilize advanced diabetes technology and neuroimaging techniques to assess brain health.
Why it matters
Potential benefit: If successful, this research could lead to strategies that prevent neurocognitive complications in children with type 1 diabetes, improving their long-term brain health and cognitive outcomes.
How similar studies have gone: Previous research has shown promising results in understanding the cognitive impacts of diabetes in children, but this specific approach focusing on early intervention is relatively novel.
Where this research is happening
-
Joslin Diabetes Center
Boston, United States Active
Researchers
- Principal investigator: Laffel, Lori M — Joslin Diabetes Center
- Study coordinator: Laffel, Lori M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.