Finding ways to improve metabolic health in people living with HIV
An Innovative Approach to Identify Correctors of Metabolic Complications in HIV
This study is looking for new treatments to help people with HIV who are dealing with weight gain and cholesterol problems caused by their medications, by testing a variety of potential drugs to find ones that can improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scripps Research Institute, the NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11011324 on NIH RePORTER |
What this research studies
This research focuses on addressing the metabolic complications that arise in individuals living with HIV, particularly those related to antiretroviral therapy. The team will utilize a high-throughput screening method to identify specific chemical compounds that can correct these metabolic issues. By analyzing a large library of potential drug candidates, they aim to find effective treatments that can help manage conditions like obesity and dyslipidemia, which are common in this population. The research involves collaboration between two prominent biomedical institutions to ensure a comprehensive approach to drug discovery.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are experiencing metabolic complications related to their condition or treatment.
Not a fit: Patients who are not living with HIV or those who do not have metabolic complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve metabolic health and reduce the risk of cardiovascular disease in people living with HIV.
How similar studies have performed: Previous research has shown promise in identifying metabolic interventions for HIV patients, but this specific approach using high-throughput screening is relatively novel.
Where this research is happening
La Jolla, United States
- Scripps Research Institute, the — La Jolla, United States (Active)
Researchers
- Principal investigator: Sanna, Pietro P — Scripps Research Institute, the
- Study coordinator: Sanna, Pietro P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.