Finding the best ways to reduce unnecessary antibiotic use in hospitals and nursing homes.

A Cluster Randomized Trial of Two Implementation Strategies to Disseminate a Successful Antibiotic Stewardship Intervention

NIH-funded research Baylor College of Medicine · NIH-11080915

This study is looking at the best ways to help doctors use antibiotics wisely for people with asymptomatic bacteriuria, a condition where bacteria are present in the bladder but there are no symptoms, to avoid unnecessary treatments.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBaylor College of Medicine NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11080915 on NIH RePORTER

What this research studies

This research investigates how to effectively implement antibiotic stewardship programs to reduce unnecessary antibiotic use, which is a significant public health threat. It focuses on a common condition called asymptomatic bacteriuria (ASB), where patients have bacteria in their bladder without symptoms, often leading to unnecessary antibiotic treatment. The study will compare two strategies for implementing guidelines: a virtual learning collaborative that promotes group learning and technical assistance that offers individualized support. By assessing these strategies, the research aims to identify the most effective way to promote better antibiotic use in real-world healthcare settings.

Who could benefit from this research

Good fit: Ideal candidates for this research include hospitalized patients and nursing home residents who may be at risk of unnecessary antibiotic treatment for asymptomatic bacteriuria.

Not a fit: Patients who do not have access to hospitals or nursing homes, or those who are not at risk for asymptomatic bacteriuria, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved antibiotic prescribing practices, ultimately preserving antibiotic effectiveness and enhancing patient safety.

How similar studies have performed: Previous research has shown that antibiotic stewardship programs can be effective, but the specific implementation strategies being tested in this study are novel.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.