NIH-funded research NIH-funded research

Finding the best way to manage airways in critically ill children before they reach the hospital

Official title: 1/2 – Pediatric Prehospital Airway Resuscitation Trial

Funded at Ohio State University · NIH-10972727 · Data updated 2026-11-12

This study is looking at the best ways to help critically ill children breathe while they are being transported in ambulances, comparing three different techniques to see which one works best in emergencies like heart problems or injuries, all to make sure paramedics can provide the best care possible.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 1, 2023
Project endJuly 31, 2029
Funding year2024
Award (this year)$1,654,060
NIH project number4UH3HL165019-02
Project IDNIH-10972727 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years who are experiencing critical conditions such as cardiac arrest, respiratory failure, or major trauma.

Less likely to help

Patients who are not critically ill or outside the age range of 0-11 years may not benefit from this research.

What this research studies

This research investigates the most effective methods for managing the airways of critically ill children in prehospital settings, such as during ambulance transport. It focuses on comparing three airway management techniques: bag-valve-mask ventilation, endotracheal intubation, and supraglottic airway insertion. By analyzing the effectiveness of these methods in various critical conditions like cardiac arrest and trauma, the study aims to improve paramedic practices and ultimately enhance patient outcomes. The research will adaptively minimize the number of patients needed for testing, ensuring efficient and ethical study design.

Why it matters

Potential benefit: If successful, this research could lead to improved airway management techniques that save the lives of critically ill children during emergencies.

How similar studies have gone: Previous research has shown varying success in airway management techniques in adults, but this specific approach in pediatric prehospital care is novel and largely untested.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Wang, Henry E. — Ohio State University
  • Study coordinator: Wang, Henry E.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.