Finding the best time to start buprenorphine treatment in jails

Assessing Optimal XR-Buprenorphine Initiation Points in Jail

['FUNDING_R01'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-10880708

This study is looking at the best way to start treatment with buprenorphine for people with opioid use disorder while they are in jail, comparing whether it's better to begin the medication when they first arrive or just before they leave, to help them stay in treatment and avoid relapse after they get out.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorNEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10880708 on ClinicalTrials.gov

What this research studies

This research investigates how to effectively initiate buprenorphine treatment for individuals with opioid use disorder (OUD) while they are incarcerated. It focuses on the timing of treatment initiation, comparing starting the medication at admission versus just before release from jail. By utilizing extended-release buprenorphine injections, the study aims to improve retention in treatment and reduce the risk of relapse and overdose after release. The research will involve monitoring participants' outcomes related to opioid use and overall health during and after their time in jail.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are incarcerated and have a diagnosis of opioid use disorder.

Not a fit: Patients who are not currently incarcerated or do not have opioid use disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for individuals with opioid use disorder, ultimately reducing relapse rates and overdose deaths.

How similar studies have performed: Previous studies have shown promising results with extended-release buprenorphine in community settings, indicating potential for success in jail-based interventions.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.