Finding the best oxygen levels for preterm infants during resuscitation
Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)
This study is looking at the best oxygen levels to help preterm babies survive and stay healthy after birth, so we can find out how to give them the right amount of oxygen during resuscitation to avoid future health problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10865108 on NIH RePORTER |
What this research studies
This research investigates the optimal oxygen saturation levels needed to improve survival rates and reduce long-term health issues in preterm infants during resuscitation at birth. The study will compare different target oxygen saturation ranges to determine which is most effective in preventing complications such as bronchopulmonary dysplasia. By analyzing data from preterm infants, the research aims to refine current guidelines for oxygen use in delivery rooms, ensuring that infants receive the right amount of oxygen to stabilize their condition without causing harm.
Who could benefit from this research
Good fit: Ideal candidates for this research are preterm infants born at less than 31 weeks of gestational age.
Not a fit: Patients who are not preterm or those who are born at or beyond 31 weeks of gestational age may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and reduced long-term health complications for preterm infants.
How similar studies have performed: Previous studies have indicated that adjusting oxygen saturation targets can significantly impact outcomes for preterm infants, suggesting that this approach has potential for success.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Kapadia, Vishal S — Ut Southwestern Medical Center
- Study coordinator: Kapadia, Vishal S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.