Finding the Best Oxygen Levels for Preterm Babies at Birth
Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)
This research aims to discover the safest and most effective oxygen levels for very premature babies right after they are born.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11126662 on NIH RePORTER |
What this research studies
When premature babies are born, they often need oxygen to help them breathe, but too much or too little oxygen can cause problems like lung issues or even affect survival. Doctors currently use oxygen targets based on healthy full-term babies, which might not be ideal for preemies. This project will compare different oxygen levels to see which ones lead to better health outcomes for these vulnerable infants. We want to make sure premature babies get just the right amount of oxygen to thrive.
Who could benefit from this research
Good fit: The ideal participants for this research would be very premature infants born at the participating medical center.
Not a fit: Full-term infants or older children would not directly benefit from this specific research focus.
Why it matters
Potential benefit: If successful, this research could lead to new guidelines for oxygen use that improve survival and reduce long-term health problems for preterm infants.
How similar studies have performed: Preliminary data from a smaller pilot study suggests that higher oxygen targets might be beneficial for preterm infants.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Kapadia, Vishal S — Ut Southwestern Medical Center
- Study coordinator: Kapadia, Vishal S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.