Finding the best combinations of therapies to cure HIV
Mathematical modeling of optimal therapeutic combinations for HIV cure
This study is looking at how to mix different treatments to find the best way to help people with HIV, so they can live healthier lives with fewer worries about the virus coming back.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10744759 on NIH RePORTER |
What this research studies
This research investigates how to combine different therapies to achieve a functional cure for HIV. By using mathematical models, the team aims to identify the most effective combinations of treatments currently being studied. The approach involves analyzing data from various therapeutic interventions to understand how they work together to suppress the virus and prevent its rebound. Patients may benefit from insights that could lead to more effective treatment strategies for HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are seeking new treatment options beyond standard antiretroviral therapy.
Not a fit: Patients who are not living with HIV or those who are not interested in experimental therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a functional cure for HIV, reducing the need for lifelong antiretroviral therapy.
How similar studies have performed: Other research has shown promise in using mathematical modeling to optimize therapeutic strategies, suggesting that this approach could be effective.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Schiffer, Joshua Tisdell — Fred Hutchinson Cancer Center
- Study coordinator: Schiffer, Joshua Tisdell
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.