Finding the best antibiotic combinations to fight resistant bacteria
Personalized Antimicrobial Combinations to Combat Resistance
['FUNDING_R01'] · UNIVERSITY OF HOUSTON · NIH-10947250
This study is working on a new way to help doctors choose the best antibiotics for patients with tough infections caused by bacteria that don't respond to many treatments, so they can get better faster.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF HOUSTON (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10947250 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a precision medicine platform to optimize the use of antibiotics against multidrug-resistant bacteria, such as Acinetobacter baumannii. By using a monitoring device and data processing algorithms, the project aims to identify effective combinations of antibiotics tailored to individual patients' bacterial infections. This approach seeks to move beyond traditional methods, which often rely on anecdotal evidence, to provide a more scientific basis for treatment decisions. Ultimately, the goal is to improve patient outcomes by ensuring that the most effective antibiotic combinations are used in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suffering from infections caused by multidrug-resistant bacteria, particularly those who have not responded to standard antibiotic treatments.
Not a fit: Patients with infections caused by bacteria that are not multidrug-resistant may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for infections caused by antibiotic-resistant bacteria, improving recovery rates and reducing complications.
How similar studies have performed: Previous research has shown promise in using combination therapies to combat antibiotic resistance, indicating that this approach could be effective.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF HOUSTON — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TAM, VINCENT H — UNIVERSITY OF HOUSTON
- Study coordinator: TAM, VINCENT H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus