Finding specific gene promoters in ticks at different life stages
Official title: Identification of stage-and tissue-specific endogenous tick promoters
Funded at University of Nevada Reno · NIH-10896405 · Data updated 2026-11-12
This study is looking at how ticks use their genes at different stages of life to help find better ways to control tick-borne diseases.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nevada Reno NIH-funded |
| Lab location | 1 site (Reno, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $237,875 |
| NIH project number | 5R21AI176352-02 |
| Project ID | NIH-10896405 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are individuals affected by tick-borne diseases or those interested in the biological mechanisms of ticks.
✕Less likely to help
Patients who are not affected by tick-borne diseases or have no interest in tick biology may not receive any benefit from this research.
What this research studies
This research investigates how to identify and analyze gene promoters in ticks, which are crucial for understanding gene expression. By using a technique called ATAC-seq, the study aims to explore the accessibility of chromatin in tick tissues and life stages, allowing researchers to pinpoint which genes are active at specific times. The approach combines chromatin analysis with RNA sequencing to uncover genes that are differentially expressed, providing insights into tick biology and potential control methods. This research could lead to advancements in managing tick-borne diseases.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of tick biology and lead to better strategies for controlling tick-borne diseases.
How similar studies have gone: Other research has shown success with similar genomic approaches in different organisms, indicating potential for this method in ticks.
Where this research is happening
-
University of Nevada Reno
Reno, United States Active
Researchers
- Principal investigator: Gulia-Nuss, Monika — University of Nevada Reno
- Study coordinator: Gulia-Nuss, Monika
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.