Finding new ways to treat small cell lung cancer
Overcoming Therapy Resistance in SCLC
This study is looking at ways to improve treatments for small cell lung cancer by understanding why some therapies don't work and how we can boost the immune system to fight the cancer better, and patients may have the chance to try new treatment combinations in the process.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11032866 on NIH RePORTER |
What this research studies
This research focuses on small cell lung cancer (SCLC), a type of lung cancer known for its poor prognosis and limited treatment options. The project aims to explore how to overcome resistance to existing therapies, particularly immunotherapies that have shown promise in other types of lung cancer. By investigating the mechanisms behind treatment resistance and the role of the immune system, the research seeks to develop more effective strategies for treating SCLC. Patients may be involved in trials that test new combinations of therapies designed to enhance the immune response against tumors.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with small cell lung cancer who have not responded adequately to standard treatments.
Not a fit: Patients with non-small cell lung cancer or those who have already exhausted all treatment options may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for small cell lung cancer, improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown success with immunotherapy approaches in other types of lung cancer, indicating potential for similar advancements in SCLC.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Akbay, Esra — Ut Southwestern Medical Center
- Study coordinator: Akbay, Esra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.