Finding new ways to treat painful nerve damage caused by chemotherapy
Identification of novel targets for the treatment of chemotherapy-induced painful peripheral neuropathy
This study is looking at the painful nerve damage that some cancer survivors experience from chemotherapy, and it's trying to find new ways to help reduce that pain so they can feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11160833 on NIH RePORTER |
What this research studies
This research focuses on chemotherapy-induced painful peripheral neuropathy (CIPN), a common side effect of cancer treatments that can severely impact the quality of life for survivors. The study aims to identify and validate specific molecular targets that contribute to this pain, using advanced techniques in biochemical analysis and imaging. By examining these targets in tumor-bearing mice, the researchers hope to develop new therapies that can either prevent or alleviate CIPN, offering hope for better pain management in cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer survivors experiencing painful peripheral neuropathy as a result of chemotherapy.
Not a fit: Patients who have not undergone chemotherapy or do not experience neuropathic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective, non-addictive treatments for patients suffering from chemotherapy-induced nerve pain.
How similar studies have performed: Previous research has shown promise in targeting similar molecular pathways for pain management, indicating potential for success in this approach.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Melemedjian, Ohannes Kevork — University of Maryland Baltimore
- Study coordinator: Melemedjian, Ohannes Kevork
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.