Finding new ways to treat pain using a new pain relief drug.

Identifying new targets in pain, utilizing the novel analgesic AS1

NIH-funded research University of Washington · NIH-11001445

This study is looking at how our bodies feel and react to pain to find better treatments for chronic pain, which many people experience, and it will test a new pain relief option called AS1 that could help with fewer side effects.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11001445 on NIH RePORTER

What this research studies

This research focuses on understanding how pain is processed in the body to develop new treatments for chronic pain, which affects over 20% of the U.S. population. The team will investigate the mechanisms behind pain perception and how emotional responses to pain can be altered. By exploring the neural circuits involved in pain and its emotional aspects, they aim to identify new therapeutic targets using a novel analgesic called AS1. This approach could lead to more effective pain relief options with fewer side effects.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from chronic pain conditions.

Not a fit: Patients with acute pain or those not experiencing chronic pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide patients with more effective pain management options that have fewer side effects than current treatments.

How similar studies have performed: Previous research has shown promise in developing new pain management strategies, indicating that this approach could lead to significant advancements.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Affective Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.