Finding new ways to prevent liver cancer
Reverse-engineering precision liver cancer chemoprevention
This study is looking for ways to prevent liver cancer by examining past patient samples and their outcomes, especially for those with non-alcoholic fatty liver disease, to find the best treatments that could help keep your liver healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10916614 on NIH RePORTER |
What this research studies
This research focuses on identifying effective targets for preventing liver cancer by analyzing archived clinical specimens and their long-term outcomes. The team will use advanced computational methods to prioritize potential chemopreventive agents and validate them through experimental studies. By understanding the molecular changes in livers affected by non-alcoholic steatohepatitis (NASH), the research aims to develop personalized prevention strategies that could lead to more effective clinical trials and improved patient management.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at high risk for liver cancer, particularly those with non-alcoholic steatohepatitis (NASH).
Not a fit: Patients without liver disease or those not at risk for liver cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative strategies for preventing liver cancer, significantly improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using similar reverse-engineering approaches to identify cancer prevention targets, suggesting potential for success in this novel application.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Hoshida, Yujin — Ut Southwestern Medical Center
- Study coordinator: Hoshida, Yujin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.