Finding new ways to prevent liver cancer
Reverse-engineering precision liver cancer chemoprevention
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10698060
This study is looking for ways to help prevent liver cancer by examining samples from patients and finding out what works best, especially for those with liver issues like non-alcoholic fatty liver disease, so that we can create tailored prevention plans to improve health outcomes.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10698060 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying effective strategies for preventing liver cancer by analyzing clinical specimens and their long-term outcomes. The team will use advanced computational methods to screen for potential chemopreventive agents and validate these findings through experimental approaches. By understanding the molecular changes associated with liver diseases like non-alcoholic steatohepatitis (NASH), the research aims to develop personalized prevention strategies that could lead to better patient management and outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at high risk for liver cancer, particularly those with non-alcoholic steatohepatitis (NASH).
Not a fit: Patients without liver disease or those who are not at risk for liver cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective liver cancer prevention strategies, improving patient outcomes and survival rates.
How similar studies have performed: Other research has shown promise in using similar reverse-engineering approaches to identify cancer prevention targets, indicating potential for success in this area.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HOSHIDA, YUJIN — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: HOSHIDA, YUJIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer