Finding new ways to fight antibiotic-resistant bacteria
Exploiting membrane targets to overcome antibiotic resistance
['FUNDING_OTHER'] · HARVARD MEDICAL SCHOOL · NIH-11130265
This study is looking for new ways to help antibiotics work better against stubborn infections caused by bacteria that have become resistant, so patients can have more effective treatments for their illnesses.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HARVARD MEDICAL SCHOOL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11130265 on ClinicalTrials.gov |
What this research studies
This research focuses on addressing the global health threat of antibiotic resistance by exploring how to disrupt the cell envelope of bacteria, which is a critical barrier for their survival. A collaborative team of scientists from various fields, including chemistry and molecular genetics, aims to identify new methods to inhibit bacterial growth and enhance the effectiveness of existing antibiotics. By targeting the processes that help bacteria maintain their protective outer layer, the research seeks to develop innovative strategies for treating infections that are currently difficult to manage due to resistance. Patients may benefit from new therapies that could restore the effectiveness of antibiotics against resistant strains of bacteria.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from infections caused by antibiotic-resistant bacteria.
Not a fit: Patients with infections that are not caused by antibiotic-resistant bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that effectively combat antibiotic-resistant infections.
How similar studies have performed: Previous research has shown promise in targeting bacterial cell envelopes to combat antibiotic resistance, indicating that this approach has potential for success.
Where this research is happening
BOSTON, UNITED STATES
- HARVARD MEDICAL SCHOOL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WALKER, SUZANNE — HARVARD MEDICAL SCHOOL
- Study coordinator: WALKER, SUZANNE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.