Finding new ways to fight antibiotic-resistant bacteria

Exploiting membrane targets to overcome antibiotic resistance

['FUNDING_OTHER'] · HARVARD MEDICAL SCHOOL · NIH-10890706

This study is looking for new ways to make antibiotics work better against stubborn bacteria that resist treatment, so that patients can have more effective options for fighting infections.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorHARVARD MEDICAL SCHOOL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10890706 on ClinicalTrials.gov

What this research studies

This research focuses on addressing the critical issue of antibiotic resistance, which poses a significant threat to public health. The team of scientists from various fields aims to explore the cell envelope of bacteria, which is a key target for developing new treatments. By disrupting the assembly and function of the bacterial cell envelope, the research seeks to enhance the effectiveness of existing antibiotics and improve patient outcomes. The approach involves innovative techniques from chemistry, biochemistry, and molecular genetics to identify new therapeutic strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from infections caused by antibiotic-resistant bacteria.

Not a fit: Patients with infections that are not caused by antibiotic-resistant bacteria may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that effectively combat antibiotic-resistant infections, improving health outcomes for patients.

How similar studies have performed: Other research has shown promise in targeting bacterial cell envelopes to combat antibiotic resistance, indicating that this approach has potential for success.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.