Finding new ways to enhance radiation treatment for cervical cancer
Official title: Identifying Novel Radiation Sensitizers in Cervical Cancer
Funded at University of Tx Md Anderson Can Ctr · NIH-10977475 · Data updated 2026-11-12
This study is looking for ways to help women with cervical cancer by finding new treatments that work better with radiation therapy, using a gentle swab to collect tissue samples to see how their bodies respond to the treatment and identify any genetic changes that could help predict their response.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | December 7, 2022 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $60,596 |
| NIH project number | 3R21CA277332-02S1 |
| Project ID | NIH-10977475 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with cervical cancer who are undergoing chemoradiation treatment.
✕Less likely to help
Patients with cervical cancer who are not receiving chemoradiation therapy may not benefit from this research.
What this research studies
This research focuses on improving outcomes for women with cervical cancer by identifying new radiation sensitizers that can enhance the effectiveness of chemoradiation therapy. Using a novel, non-invasive swab-based biopsy method, researchers will collect tissue samples before, during, and after treatment to analyze genetic changes associated with treatment response. The study aims to validate specific genetic mutations that may predict how well patients respond to therapy and to develop a platform for testing new targeted treatments based on these findings.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for cervical cancer, potentially reducing relapse rates and improving survival outcomes.
How similar studies have gone: Previous research has shown promise in using genetic profiling to enhance cancer treatment, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Colbert, Lauren Elizabeth — University of Tx Md Anderson Can Ctr
- Study coordinator: Colbert, Lauren Elizabeth
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.