Finding new ways to enhance radiation treatment for cervical cancer
Identifying Novel Radiation Sensitizers in Cervical Cancer
This study is looking for better ways to treat cervical cancer by finding new medicines that can make radiation therapy work even better, using a gentle swab to collect tissue samples from patients before, during, and after their treatment, so they can discover important changes in the tumors and create more personalized treatment plans just for them.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10749921 on NIH RePORTER |
What this research studies
This research focuses on improving treatment outcomes for cervical cancer patients by identifying new radiation sensitizers. It utilizes a non-invasive swab-based biopsy method to collect tissue samples before, during, and after chemoradiation, minimizing discomfort and risks associated with traditional biopsies. The study aims to analyze genetic changes in tumors during treatment to discover mutations that could be targeted with new therapies. By validating these findings in a larger patient population, the research seeks to develop personalized treatment options for cervical cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with cervical cancer who are undergoing chemoradiation treatment.
Not a fit: Patients with early-stage cervical cancer who are not receiving chemoradiation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for cervical cancer, potentially reducing relapse rates and improving survival outcomes.
How similar studies have performed: Other research has shown promise in using genetic profiling to enhance cancer treatment, suggesting that this approach could yield significant advancements.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Colbert, Lauren Elizabeth — University of Tx Md Anderson Can Ctr
- Study coordinator: Colbert, Lauren Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.