Finding new ways to diagnose neglected tropical diseases.
Official title: NOVEL DIAGNOSTIC BIOMARKERS DISCOVERY AND VALIDATION FOR SELECT NEGLECTED TROPICAL DISEASES
Funded at Kephera Diagnostics, LLC · NIH-11307400 · Data updated 2026-11-12
This study is looking for new ways to quickly and accurately diagnose neglected tropical diseases caused by a parasite called T. cruzi, so that patients can get the right treatment sooner.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kephera Diagnostics, LLC NIH-funded |
| Lab location | 1 site (Framingham, UNITED STATES) |
| Project start | December 1, 2024 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $300,000 |
| NIH project number | 75N93025C00003-0-9999-1 |
| Project ID | NIH-11307400 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for or showing symptoms of neglected tropical diseases caused by T. cruzi.
✕Less likely to help
Patients with diseases not related to T. cruzi or those who do not exhibit symptoms of neglected tropical diseases may not benefit from this research.
What this research studies
This research focuses on discovering and validating new diagnostic biomarkers for neglected tropical diseases, particularly those caused by the American trypanosome, T. cruzi. By identifying specific biological markers, the project aims to improve the accuracy and speed of diagnosing these diseases, which are often overlooked. The methodology involves rigorous testing and validation processes to ensure that the biomarkers are reliable and effective for clinical use. Patients may benefit from earlier and more accurate diagnoses, leading to timely treatment.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools that enable earlier detection and treatment of neglected tropical diseases.
How similar studies have gone: Previous research has shown promise in developing diagnostic biomarkers for other diseases, suggesting potential success for this novel approach.
Where this research is happening
-
Kephera Diagnostics, LLC
Framingham, United States Active
Researchers
- Principal investigator: Levin, Andrew E. — Kephera Diagnostics, LLC
- Study coordinator: Levin, Andrew E.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.