Finding new ways to diagnose neglected tropical diseases.
Official title: NOVEL DIAGNOSTIC BIOMARKERS DISCOVERY AND VALIDATION FOR SELECT NEGLECTED TROPICAL DISEASES
Funded at Big Eye Diagnostics, INC. · NIH-11306897 · Data updated 2026-11-12
This study is looking for new ways to help doctors find and diagnose certain tropical diseases caused by parasites, so that patients can get the right treatment more easily and quickly.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Big Eye Diagnostics, INC. NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $299,986 |
| NIH project number | 75N93025C00005-0-9999-1 |
| Project ID | NIH-11306897 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are at risk for or have been diagnosed with neglected tropical diseases.
✕Less likely to help
Patients with non-parasitic diseases or those not affected by neglected tropical diseases may not receive any benefit from this research.
What this research studies
This research focuses on discovering and validating new diagnostic biomarkers for neglected tropical diseases, specifically targeting conditions caused by parasites like Loa loa and Onchocerca volvulus. The approach involves identifying unique biological markers that can help in the early detection and accurate diagnosis of these diseases. By utilizing advanced diagnostic techniques, the research aims to improve the reliability and accessibility of testing for affected populations. Patients may benefit from more accurate diagnoses, leading to better treatment options and outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and accessible diagnostic tests for neglected tropical diseases, improving patient care.
How similar studies have gone: Other research has shown promise in developing novel diagnostics for tropical diseases, indicating a potential for success in this area.
Where this research is happening
-
Big Eye Diagnostics, INC.
San Diego, United States Active
Researchers
- Principal investigator: Perez, Rhea — Big Eye Diagnostics, INC.
- Study coordinator: Perez, Rhea
Related research
Other NIH-funded projects on the same topics.
-
A low-cost test for diagnosing Hepatitis B, Hepatitis C, and HIV infections.
This study is working on a simple test that you can use at home to check for Hepatitis B, Hepatitis C, and HIV, making it easier for people, especially in areas with fewer resources, to get the health care they need.
-
Rapid, ultra-sensitive test for detecting lymphatic filariasis
This project is making an inexpensive, easy-to-use rapid strip test to find early Wuchereria bancrofti infections so people and health teams in affected communities can detect and act sooner.
-
A rapid test to detect lymphatic filariasis infections
This study is working on a new, easy-to-use test that can quickly and accurately detect lymphatic filariasis, a disease caused by a parasite, to help communities monitor and manage the disease better, especially after treatment programs.
-
A new rapid test for Brugia parasite infection
This project is developing a quick and accurate test to find Brugia parasite infections, which cause lymphatic filariasis, to help eliminate the disease.
-
Developing a new rapid test for river blindness diagnosis
This study is working on a quick and accurate test for river blindness to help health organizations better target treatments for those affected, and it will involve around 10,000 people to make sure the test works well in real life.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.