Finding new ways to diagnose and understand heart transplant complications.

Identifying Novel Diagnostics and Mechanisms for Cardiac Allograft Vasculopathy

NIH-funded research Columbia University Health Sciences · NIH-10813878

This study is all about finding better ways to diagnose and understand cardiac allograft vasculopathy (CAV), a condition that can affect people who have had heart transplants, so that doctors can help heart transplant patients live healthier lives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10813878 on NIH RePORTER

What this research studies

This research focuses on improving the diagnosis and understanding of cardiac allograft vasculopathy (CAV), a serious condition that can affect heart transplant recipients. Led by Dr. Kevin Clerkin, a cardiologist specializing in heart failure and transplants, the project aims to identify the mechanisms behind CAV and enhance diagnostic methods. The research involves a multidisciplinary approach, including collaboration with experts in transplant immunology and cardiac imaging, to develop better strategies for managing this condition. By improving our understanding of CAV, the research seeks to lay the groundwork for future therapies that could benefit heart transplant patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have undergone heart transplantation and are at risk for cardiac allograft vasculopathy.

Not a fit: Patients who have not received a heart transplant or those with other unrelated cardiac conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment options for heart transplant recipients, potentially reducing the risk of complications and improving patient outcomes.

How similar studies have performed: Previous research has shown promise in improving diagnostics and understanding of transplant-related complications, indicating that this approach has the potential for success.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.