Finding new ways to develop medicines for diseases that are hard to treat

Expanding the chemical probe development paradigm toward underexplored targets

NIH-funded research Albert Einstein College of Medicine · NIH-11138652

This research aims to speed up the process of discovering new medicines, especially for diseases where current treatments are limited.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAlbert Einstein College of Medicine NIH-funded
Lab location1 site (Bronx, United States)
Project IDNIH-11138652 on NIH RePORTER

What this research studies

Our bodies have many proteins that play a role in disease, but it's often hard to create drugs that specifically target them. This project is developing new chemistry methods to more quickly find and improve molecules that can interact with these 'underexplored' disease targets. By using a special high-speed chemistry platform, we hope to make it easier to discover potential new drugs. This work focuses on creating better tools for drug discovery, which could lead to new treatments for various conditions.

Who could benefit from this research

Good fit: This foundational research does not involve direct patient participation, but future patients with diseases currently lacking good treatments could potentially benefit from its outcomes.

Not a fit: Patients seeking immediate treatment options will not directly benefit from this early-stage drug discovery research.

Why it matters

Potential benefit: If successful, this work could significantly accelerate the discovery of new drugs for diseases that currently lack effective treatments.

How similar studies have performed: The research builds upon a 'first-of-its-kind' chemistry platform that has shown success with model proteins, and this project aims to expand its application to more challenging disease targets.

Where this research is happening

Bronx, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.